Biotechnology and biopharmaceuticals : transforming proteins and genes into drugs / Rodney J.Y. Ho, Milo Gibaldi.
By: Ho, Rodney J. Y.
Contributor(s): Gibaldi, Milo.Material type: BookCall no.: MED QV 2013 642571Publication: Hoboken, N.J. : Wiley-Blackwell, c2013Edition: 2nd ed.Description: xxvi, 698 p.,  p. of plates : ill. (some col.).ISBN: 9781118179796 ; 111817979X .Subject(s): Biopharmaceutics | Chemistry, Pharmaceutical | Drug design
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Includes bibliographical references and index.
Introduction to biopharmaceuticals -- Distinctions of biologic versus small molecule platforms in drug development -- Financing biologic drug development -- Application of biotechnology in drug discovery and early development -- Large-scale production of recombinant proteins -- Clinical pharmacology, toxicology, and therapeutic dosage & response -- Clinical evaluation and regulatory approval & enforcement of biopharmaceuticals -- Pharmacoeconomics and drug pricing / Garrison -- Antibodies and derivatives -- Hematopoietic growth and coagulation factors -- Cytokines and interferons -- Hormones -- Enzymes -- Vaccines / Hu, Ho -- Other biopharmaceutical products -- Advances in personalized medicine : pharmacogenetics in drug therapy -- Gene and cell therapy -- Integration of discovery and development: the role of genomics, proteomics, and metabolomics -- Pharmacoeconomics, outcome, and health technology assessment research in drug development -- Future prospects.
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